Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1982-07-06
1984-05-08
Schwartz, Richard A.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
2602433, 4242484, 42424851, 42424858, 424250, 424256, 546261, 546262, 546284, 546307, C07D47104
Patent
active
044473613
ABSTRACT:
Pyrido[1,4]benzodiazepines having antidepressant activity of the formula ##STR1## wherein Ar is 2, 3 and 4-pyridinyl, 2 or 3-thienyl, phenyl or a substituted phenyl; R is hydrogen, loweralkyl or an amine on the end of a hydrocarbon chain; Z is hydrogen, halogen, trifluoromethyl, loweralkyl, loweralkoxy, hydroxy or nitro; and Y is hydrogen, loweralkyl, loweralkoxy or hydroxy; and the pharmaceutical salts are prepared from [2-[(aminopyridinyl)amino]phenyl]arylmethanones which also have antidepressant activity.
REFERENCES:
Chemical Abstracts, 79:5388v (1973) [Japan 73 11,110, Ozawa et al., 4/10/73].
Chemical Abstracts, 84:164876a (1976) [Japan Kokai No. 76 06,991, Kobayashi et al., 1/20/76].
A. H. Robins Company, Inc.
Schwartz Richard A.
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