Aryl substituted pyridines and the use thereof

Details Aryl substituted pyridines and the use thereof Aryl substituted pyridines and the use thereof

2006-09-11

2009-08-25

Solola, Taofiq A (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C546S339000

Reexamination Certificate

active

07579367

ABSTRACT:
This invention relates aryl substituted pyridines of Formula I:or a pharmaceutically acceptable salt, prodrug or solvate thereof, wherein Ar and R1-R4are set in the specification. The invention is also directed to the use of compounds of Formula I for the treatment of neuronal damage following global and focal ischemia, for the treatment or prevention of neurodegenerative conditions such as amyotrophic lateral sclerosis (ALS), and for the treatment, prevention or amelioration of both acute or chronic pain, as antitinnitus agents, as anticonvulsants, and as antimanic depressants, as local anesthetics, as antiarrhythmics and for the treatment or prevention of diabetic neuropathy.

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