Aryl-substituted naphthyridine and pyridopyrazine derivatives an

Details Aryl-substituted naphthyridine and pyridopyrazine derivatives an Aryl-substituted naphthyridine and pyridopyrazine derivatives an

1989-06-26

1991-04-30

Sutto, Anton H.

Drug, bio-affecting and body treating compositions

Dermatitis

Eczema

514183, 514210, 514215, 514241, 514245, 514253, 514254, 514269, 514293, 514864, 514863, 514249, 540471, 540557, 546 82, 544215, 544216, 544238, 544322, 544328, 544333, 544345, 544405, A61K 31435, A61K 31495, C07D47104, C07D25112

Patent

active

050118609

ABSTRACT:
Aryl-substituted naphthyridines and pyridopyrazines are disclosed which are useful in treating allergic reactions, inflammation, peptic ulcers and/or hyperproliferative skin disease. Pharmaceutical compositions and methods of treatment employing such compounds are also disclosed.

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Kaneko et al., Chem. Pharm. Bull., 17, (6), 1290, (1969).
Fournier et al., Bull. LaSociete Chim. deFrance, 364, (1968).
Goodman et al., (editors), The Pharmacology Basis of Therapeutics, sixth edition, MacMillan Publishing Co., p. 28.
Hawkins et al., J. Chem. Soc., Perkin Trans., I, (1983), pp. 2077-2087.

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