Aryl-substituted derivatives of cycloalkyl and branched...

Details Aryl-substituted derivatives of cycloalkyl and branched... Aryl-substituted derivatives of cycloalkyl and branched...

2004-12-28

2008-08-26

Wilson, James O. (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C544S297000

Reexamination Certificate

active

07417048

ABSTRACT:
Novel peripheral antinociceptive compounds are disclosed having a pharmacophore unit that target small-diameter nerve fibers that transmit signals of pain and discomfort from the soma and viscera. By acting on this target, the pharmacophore unit obtunds pain and diminishes hyper-reflexia from organs such as the skin, the respiratory tract, the corpus, the lower urinary tract, and the bowel. The pharmacophore unit is coupled to substituents that facilitate delivery of the pharmacophore to its target.

REFERENCES:
patent: 4193936 (1980-03-01), Watson et al.
patent: 4318900 (1982-03-01), Rowsell et al.
patent: 5009893 (1991-04-01), Cherukuri et al.
patent: 5244670 (1993-09-01), Upson et al.
patent: 5698181 (1997-12-01), Luo et al.
patent: 6497859 (2002-12-01), Zanone et al.
patent: 6784266 (2004-08-01), Kim et al.
patent: 1457671 (1976-12-01), None

Affiliated with

Also associated with

Rating

Aryl-substituted derivatives of cycloalkyl and branched... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Aryl-substituted derivatives of cycloalkyl and branched..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Aryl-substituted derivatives of cycloalkyl and branched... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4015388