Aryl-substituted benzocycloalkyl-derived anti-atherosclerotic ag

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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549292, A61K 3135, C07D30930

Patent

active

051149648

ABSTRACT:
Disclosed are novel aryl-substituted benzocycloalkyl-derived 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors useful as antihypercholesterolemic agents represented by the formula: ##STR1## their corresponding dihydroxy acids, and pharmaceutically acceptable salts thereof.

REFERENCES:
patent: 4499289 (1985-02-01), Baran
patent: 4804679 (1989-02-01), Anderson
patent: 4863957 (1989-09-01), Neuenschwander
patent: 4892884 (1990-01-01), Neuenschwander

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