Aryl substituted aminomethyl benzene derivatives

Details Aryl substituted aminomethyl benzene derivatives Aryl substituted aminomethyl benzene derivatives

1985-12-27

1988-07-05

Brust, Joseph Paul

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514438, 514445, 514447, 514448, 546187, 546213, 548524, 548527, 549 65, 549 69, 549 71, 549 72, 549 77, C07D29510, A61K 3140, A61K 31395, A61K 3138

Patent

active

047555270

ABSTRACT:
The present invention relates to new compounds of the formula ##STR1## where X is ##STR2## alkylene, or --S--where R.sub.1 is hydrogen, alkyl, or aryl; W is hydrogen, hydroxy, amino, alkyloxy, aryloxy, O-alkyl, or O-aralkyl; (Y).sub.A) is --CH.sub.2 NR.sub.2 R.sub.3 where R.sub.2 and R.sub.3 may be hydrogen, substituted alkyls, aryls, or together with N form a 5 to 7 membered heterocyclic group; and Ar is a substituted or unsubstituted aryl. These compounds are useful in the treatment of various cardiac arrhythmias.

REFERENCES:
patent: 3285912 (1966-11-01), Palopoli et al.
patent: 3287363 (1966-11-01), Palopoli et al.
patent: 4305940 (1981-12-01), Quadro
patent: 4323691 (1982-04-01), Ours et al.
patent: 4362738 (1982-12-01), Keck et al.
patent: 4562201 (1985-12-01), Stout et al.
Sun Cunji et al., Yao Hsueh Hsueh Pao, vol. 16, (1981), pp. 564-570.
Boucherle et al., Chimie Therapeutique, (1967), pp. 410-414.
Li, et al., C.A., 92 (1980), 121950t.

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