Aryl substituted 1H-4,5-dihydro-1,2,3-triazoles as anticonvulsan

Details Aryl substituted 1H-4,5-dihydro-1,2,3-triazoles as anticonvulsan Aryl substituted 1H-4,5-dihydro-1,2,3-triazoles as anticonvulsan

1984-07-10

1986-10-21

Fan, Jane T.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548255, C07D40104

Patent

active

046186816

ABSTRACT:
Anticonvulsant compositions comprise as the active ingredient a compound selected from the group consisting of those of the formulae: ##STR1## wherein R.sub.1 is o-chlorophenyl, o-nitrophenyl, 2,4- or 2,6-dichlorophenyl, 4-pyridyl, 3-pyridyl, 2-pyridyl, or 2-quinolyl, and R.sub.2 is hydrogen, m- or p-trifluoromethyl, m-chloro-p-fluoro, p-methyl, p-ethyl, m- or p-chloro, m-nitro, p-bromo, p-fluoro, or p-COOR.sub.3, wherein R.sub.3 is lower alkyl of 1 to 4 carbon atoms. The compositions are administered to mammals in an amount to provide a dosage amount ranging from about 30 mg/kg to 300 mg/kg.

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