Aryl spirohydantoin CGRP receptor antagonists

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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Details

C514S278000, C514S369000, C514S389000, C544S230000, C546S015000, C548S147000, C548S301100

Reexamination Certificate

active

10547227

ABSTRACT:
The present invention is directed to compounds that are antagonists of CGRP receptors and that are useful in the treatment or prevention of diseases in which the CGRP is involved, such as headache, migraine and cluster headache. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.

REFERENCES:
patent: 0159143 (1985-10-01), None
Pinder et al. (J. Med. Chem. 1971, 14(9), 892-893. ** Indicates that the CAS Abstract and Structures are provided.

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