Aryl phenylhydrazides as selective COX-2 inhibitors for treatmen

Details Aryl phenylhydrazides as selective COX-2 inhibitors for treatmen Aryl phenylhydrazides as selective COX-2 inhibitors for treatmen

1999-10-20

2000-06-20

Jarvis, William R. A.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

A61K 3116

Patent

active

060778695

ABSTRACT:
This invention relates to the use of compounds of formula I as selective COX-2 inhibitors and antiinflammatory agents: ##STR1## wherein: X and Y are selected from hydrogen, halogen, alkyl, nitro, amino or other oxygen and sulfur containing functional groups such as hydroxy, methoxy and methylsulfonyl.

REFERENCES:
Ghiglieri-Bertez et al, European Journal of Medicinal Chemistry, vol. 22, pp. 147-152, 1987.

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