Aryl or heteroaryl amide compounds

Details Aryl or heteroaryl amide compounds Aryl or heteroaryl amide compounds

2007-07-03

2007-07-03

Davis, Zinna N. (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S340000, C514S354000, C514S616000, C546S255000, C546S268400, C546S315000, C564S155000

Reexamination Certificate

active

10932463

ABSTRACT:
This invention provides a compound of the formula (I):wherein A represents a phenyl group or the like: B represents an aryl or the like: E represents a 1,4-phenylene group; R1and R2independently represent a hydrogen atom or the like: R3and R4independently represent a hydrogen atom or the like: R5represents —CO2H or the like: R6represents an alkyl group having from 1 to 6 carbon atoms or the like: X represents a methylene group or the like. These compounds are useful for the treatment of disease conditions mediated by prostaglandin such as pain, or the like in mammalian. This invention also provides a pharmaceutical composition comprising the above compound.

REFERENCES:
patent: 4181658 (1980-01-01), Hitzel et al.
patent: 4221815 (1980-09-01), Weyer et al.
patent: 25 00 157 (1976-07-01), None
patent: 27 06 977 (1978-08-01), None
patent: 1 229 034 (2002-01-01), None
patent: WO 98/45268 (1998-10-01), None
patent: WO 00/64876 (2000-11-01), None
patent: WO 03/016254 (2003-02-01), None

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