Aryl imidazolyl vinyl ethers and processes for using same

Details Aryl imidazolyl vinyl ethers and processes for using same Aryl imidazolyl vinyl ethers and processes for using same

1978-12-18

1980-07-01

Trousof, Natalie

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

542405, 542411, 542413, 542426, 542453, 542458, 548336, 548337, 548338, 548341, A61K 31415, C07D23360

Patent

active

042106575

ABSTRACT:
Aryl-imidazol-1-yl vinyl ethers and their acid addition salts are disclosed, wherein the imidazolyl vinyl ether has the formula: ##STR1## Ar in the formula represents a substituted or unsubstituted aryl or heterocyclic radical; R represents hydrogen or a C.sub.1 -C.sub.12 alkyl or cycloalkyl (saturated or unsaturated) or Ar as above; Im represents a 1-H-imidazol-1-yl group (unsubstituted or substituted); and Y represents a saturated or unsaturated, acyclic or cyclic C.sub.1 -C.sub.12 alkyl, or aryl or aralkyl, or an alkyl or alkylene residue directly bound to the ether oxygen and having a chain once or twice interrupted by --O--, --S--, --SO-- or --SO.sub.2 -- bridges. These compounds are effective wide spectrum fungicides and bactericides.

REFERENCES:
patent: 3462446 (1969-08-01), De Wald
patent: 3658797 (1972-04-01), Ross et al.
patent: 3658813 (1972-04-01), Godefroi et al.
patent: 3839574 (1974-10-01), Godefroi et al.
patent: 4086351 (1978-04-01), Balasubramanyan
Hofmann Imidazoles and Its Derivatives, Part I, p. 127, N.Y., Interscience, 1953.
Godefroi et al., J. Med. Chem., 1969, vol. 12, pp. 784-791.

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