Aryl group- or aromatic heterocyclic group-substituted aminoquin

Details Aryl group- or aromatic heterocyclic group-substituted aminoquin Aryl group- or aromatic heterocyclic group-substituted aminoquin

1994-11-15

1996-05-21

Shah, Mukund J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514218, 5142335, 5142345, 514254, 514300, 514312, 544121, 544122, 544295, 544363, 540575, 540597, 546122, 546123, 546153, 546156, A61K 3147, A61K 31495, C07D215227, C07D215233

Patent

active

055190162

ABSTRACT:
Disclosed are an aryl group- or heterocyclic group-substituted aminoquinolone compound represented by the formula (Ia), (Ib) or (Ic): ##STR1## wherein each of the substitutents are defined in the specification, or a salt of the compound, and an AIDS curing agent containing the same as an effective ingredient.

REFERENCES:
patent: 4840956 (1989-06-01), Domagala et al.
patent: 4880806 (1989-11-01), Ueda et al.
patent: 5086649 (1992-02-01), Kise et al.
patent: 5210193 (1993-05-01), Sum et al.
patent: 5217972 (1993-06-01), Grohe et al.
Elrod et al., Journal of Chromatography, 519(1) 125-136, 1990.
Ruprecht et al., AIDS Research and Human Retroviruses, 8(6) 1992 pp. 997-1011.
"AIDS, The Unanswered Questions", Science 260, 1253-1293, J. Benditt, ed., 28 May 1993.
Chemical Abstracts, vol. 114, 1991 Abstract No. 247292, "Preparation of 4-oxo-3-quinolonecarboxylic acids and 4-oxo-1,8 naphthyridine-3-carboxylic acids as antiviral agents" of JP 02,264,724.
Junko Nozaki-Renard et al, "A Fluoroquinolone (DR-3355) protects human lymphocyte cell lines from HIV-1-induced cytotoxicity", (1990), vol. 4, No. 1, pp. 1283-1286, AIDS.

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