Aryl fatty acid leukotriene synthesis inhibitors

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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260408, 2604109N, 2604109R, 260413, 260399, 568 59, 568662, 568812, 568813, 568765, 568766, 514549, 514560, 514627, 514730, C07C 5742, C07C 69108, C07C10376, C07C 3330

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045644764

ABSTRACT:
Aryl fatty acid compounds of the formula (I) ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, X, and Y are as defined herein are novel and useful in the treatment of allergic and inflammatory disorders.

REFERENCES:
"Synthesis and 5-Lipoxygenase Inhibitory Activity of 7,7-Dimethyleicosa-5Z,8Z-Dienoic Acid" by J. Ackroyd et al. which appeared in Tetrahedron Letters, vol. 24, No. 46, pp. 5139-5140 (1983).

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