Aryl, aryloxy, and aklyloxy substituted 1 H -indol-3-yl...

Details Aryl, aryloxy, and aklyloxy substituted 1 H -indol-3-yl... Aryl, aryloxy, and aklyloxy substituted 1 H -indol-3-yl...

2007-08-21

2007-08-21

Shameem, Golam M. M. (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C548S469000, C548S490000, C548S491000, C548S127000, C514S415000, C546S268100, C546S277400

Reexamination Certificate

active

10731308

ABSTRACT:
Compounds of formula I are provided:wherein:R1, R2, and R3, are as defined herein, as well as pharmaceutical composition and methods using the compounds as inhibitors of plasminogen activator inhibitor (PAI-1) and as therapeutic composition for treating conditions resulting from fibrinolytic disorders, such as deep vein thrombosis, coronary heart disease and pulmonary fibrosis.

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