Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2006-10-24
2006-10-24
Chang, Celia (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S653000, C546S157000
Reexamination Certificate
active
07125892
ABSTRACT:
The invention provides novel β2adrenergic receptor agonist compounds of formula (I):wherein R1–R13and w have any of the values described in the specification. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with β2adrenergic receptor activity, and processes and intermediates useful for preparing such compounds.
REFERENCES:
patent: 4894219 (1990-01-01), Baker et al.
patent: 5750701 (1998-05-01), Beeley et al.
patent: 6265581 (2001-07-01), Bell et al.
patent: 6541669 (2003-04-01), Moran et al.
patent: 6576793 (2003-06-01), Moran et al.
patent: 6653323 (2003-11-01), Moran et al.
patent: 6670376 (2003-12-01), Moran et al.
patent: 2002/0022625 (2002-02-01), Walland et al.
patent: 849.794 (1977-04-01), None
patent: 0 147 719 (1985-07-01), None
patent: 52-83379 (1977-07-01), None
patent: WO 95/25104 (1995-09-01), None
patent: WO 00/75114 (2000-12-01), None
patent: WO 01/07026 (2001-02-01), None
patent: WO 01/35947 (2001-05-01), None
patent: WO 01/83462 (2001-11-01), None
patent: WO 02/38544 (2002-05-01), None
Riley et al. “Synergistic activity . . . ” CA 107:211584 (1987).
Tsuzurahara et al. “Antiallergic effects . . . ” CA 91:186691 (1979).
Deyrup et al., “Structure-affinity profile of 8-hydroxycarbostyril-based agonists that dissociate slowly from the β2-adrenoceptor”, Naunyn-Schmiedeberg's Arch Pharmacol, vol. 359: pp. 168-177 (1999).
Isogaya et al., “Binding Pockets of the β1- and β2-Adrenergic Receptors for Subtype-Selective Agonists”, Molecular Pharmacology, vol. 56, pp. 875-885 (1999).
Milecki et al., “Carbostyril Derivatives Having Potent β-Adrenergic Agonist Properties”, vol. 30, pp. 1563-1566, 1987.
Yoshizaki et al., “Sympathomimetic Amines Having a Carbostyril Nucleus”, vol. 19, No. 9, pp. 1138-1142 (1976).
Aggen James
Jacobsen John R.
Moran Edmund J.
Chang Celia
Hagenah Jeffrey A.
Saxon Roberta P.
Theravance Inc.
LandOfFree
Aryl aniline β 2 adrenergic receptor agonists does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Aryl aniline β 2 adrenergic receptor agonists, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Aryl aniline β 2 adrenergic receptor agonists will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3664993