Aryl and heteroarylmethoxyphenyl inhibitors of leukotriene biosy

Details Aryl and heteroarylmethoxyphenyl inhibitors of leukotriene biosy Aryl and heteroarylmethoxyphenyl inhibitors of leukotriene biosy

1993-06-02

1994-10-25

Springer, David B.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514314, 514507, 514351, 558 6, 558299, 546265, 546175, C07D21514, C07D21330, A61K 3147, A61K 3144

Patent

active

053589556

ABSTRACT:
The present invention relates to a compound of the formula ##STR1## or a pharmaceutically acceptable salt thereof wherein W is selected from optionally substituted pyridyl, naphthyl, and quinolyl; which inhibits lipoxygenase enzyme activity and leukotriene biosynthesis and is useful in the treatment of inflammatory disease states; also disclosed are leukotriene biosynthesis inhibiting compositions and a method for inhibiting lipoxygenase enzyme activity and leukotriene biosynthesis.

REFERENCES:
patent: 4507148 (1985-03-01), Carter
patent: 4970215 (1990-11-01), Mohrs et al.

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