Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2006-06-13
2006-06-13
Kifle, Bruck (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C540S556000
Reexamination Certificate
active
07060699
ABSTRACT:
The present invention relates to novel aryl and heteroaryl diazabicycloalkane derivatives, which are found to be cholinergic ligands at the nicotinic acetylcholine receptors and modulators of the monoamine receptors and transporters. Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system (CNS), the peripheral nervous system (PNS), diseases or disorders related to smooth muscle contraction, endocrine diseases or disorders, diseases or disorders related to neuro-degeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by the termination of abuse of chemical substances.
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Jensen et al., Journal of Labelled Compounds and Radiopharmaceuticals, J Label Compd Radiopharm 2002, 45: pp. 181-189.
Ahring Philip K.
Jørgensen Tino Dyhring
Nielsen Elsebet Østergaard
Nielsen Simon Feldbæk
Olsen Gunnar M
Birch & Stewart Kolasch & Birch, LLP
Kifle Bruck
Neurosearch A/S
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