Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2005-10-04
2005-10-04
Desai, Rita (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S454000, C514S352000, C544S366000, C544S367000, C548S427000, C549S458000
Reexamination Certificate
active
06951880
ABSTRACT:
This invention provides novel compounds possessing antibacterial and/or antifungal and/or antitumor activity. Pharmaceutical compositions containing these compounds, methods of making and methods for using these compounds are also provided.
REFERENCES:
patent: 5760069 (1998-06-01), Lukas-Laskey et al.
patent: 6294565 (2001-09-01), Dykstra et al.
patent: 6326395 (2001-12-01), Tidwell et al.
patent: 6635668 (2003-10-01), Tidwell et al.
patent: 2002/0019437 (2002-02-01), Boykin et al.
Takiguchi et al., 1988, CAS: 108:213874.
Assy et al., 1995, CAS: 124:176041.
Akalayeva et al., 1995, CAS:123:251041.
Bally, Christian, et al., Sequence-Specific DNA Minor Groove Binders, Design and Synthesis of Netropsin and Distamycin Analogues,Bioconjugate Chemistry, vol. 9, No. 5, (Sep./Oct. 1998), pp. 513-538.
Fillpowsky, Mark E., et al., Linked Lexitropsins and the in Vitro Inhibition of HIV-1 Reverse Transcriptase RNA-Directed DNA Polymerizaton: A Novel Induced-Fit of 3.5 m-Pyridyl Bisdistamycin to Enzyme-Associated Template-Primer,Biochemistry, (Dec. 3, 1996), 35:40, pp. 15399-15410.
Kissinger et al., Molecular Recognition between Oilgopeptides and Nucleic Acids: DNA Binding Specificity of a Series of Bis Netropsin Analogues Deduced from Footprinting Analysis,Chem. Res. Toxicol., 3(2), (1990), pp. 162-168.
Neamati, Nouri et al., Highly Potent Synthetic Polyamides, Bisdistamycins, and Lexitropsins as Inhibitors and Human Immunodeficiently Virus Type 1 Integrase,Molecular Pharmacology, 54, (1998), pp. 280-290.
Wang, Z., et al., Effects of Bifunctional Netropson-related Minor Groove-binding Ligands on Mammallan Type I DNA Topolsomarase.,Biochem. Pharmacol., 53, (1997), pp. 309-316.
Buchwald, et al., A Highly Active Catalyst for Palladium-Catalyzed Cross-Coupling Reactions: Room-Temperature Suzuki Couplings and Amination of Unactivated Aryl Chlorides.,J. Am. Chem. Soc., 120, (1998), pp. 9722-9723.
Tidwell, R., et al., Anti-Pneumocystis carinil pneumonia activity of dicationic carbazoles,Eur. J. Med. Chem.,32, (1997), pp. 781-793.
Tidwell, R., et al., Dicationic dibenzofuran derivatives as anti-Pneumocystis carinilpneumonia agents: synthesis, DNA binding affinity, and anti-P, carinil activity in an immunosuppressed rat model,Eur. J. Med. Chem., 34, (1999), pp. 215-224.
Bally, et al., Distribution of Furamidine Analogues in Tumor Cells: Influence of the Number of Positive Charges,J. Med. Chem., 45(10), (2002), pp. 1994-2002.
Tidwell, Richard R., et al., Comparative efficacy evaluation of dicationic carbazole compounds, nitazoxanide, and paromomycin againstCrytoaporidium parvuminfections in a neonatal mouse model.,Antimicrob. Agents Chemother., (1998), 42(11). pp. 2877-2882.
Perfect, John R., et al., In vitro antifungal activities of a series of dication-substituted carbazoles, furans, and benzimidazoles,Antimicrob. Agents Chemother, (1998), 42(10), pp. 2503-2510.
Gezginci Mikail Hakan
Keicher Jesse Daniel
Roberts Christoher Don
Velligan Mark Douglas
Desai Rita
Genelabs Technologies, Inc.
Shiao Robert
Yang Junrui
LandOfFree
Aryl and heteroaryl compounds as antibacterial and... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Aryl and heteroaryl compounds as antibacterial and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Aryl and heteroaryl compounds as antibacterial and... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3448525