Aryl alkenoic acid derivatives as leukotriene antagonists

Details Aryl alkenoic acid derivatives as leukotriene antagonists Aryl alkenoic acid derivatives as leukotriene antagonists

1992-08-12

1993-11-30

Dees, Jose G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Fatty compounds having an acid moiety which contains the...

554 42, 554101, 554213, 554218, 554219, 554220, 554223, 554 85, 554115, 554116, 554121, 560 9, 560 37, 560 55, 560101, 560147, 560155, 560171, 560181, C07C23500

Patent

active

052667138

ABSTRACT:
Aryl alkenoic acid derivatives, and physiologically acceptable salts thereof, are provided which are potent leukotriene antagonists and may be used for the treatment of circulatory diseases and preferably for respiratory diseases such as asthma. The derivatives have a general formula I ##STR1## in which X is --S--,

REFERENCES:
patent: 4775662 (1988-10-01), Gleason
Bernstein et al, Journal of Medicinal Chemistry vol. 31, 1988, pp. 692-696.

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