Organic compounds -- part of the class 532-570 series – Organic compounds – Pteroyl per se or having -c- – wherein x is chalcogen – bonded...
Reexamination Certificate
2008-04-01
2008-04-01
Richter, Johann R. (Department: 1616)
Organic compounds -- part of the class 532-570 series
Organic compounds
Pteroyl per se or having -c-, wherein x is chalcogen, bonded...
C514S259100, C514S259300, C514S259310, C514S923000, C544S224000, C544S236000, C544S242000, C544S255000, C544S256000, C544S262000, C544S281000, C546S001000, C546S255000, C546S268100, C546S290000
Reexamination Certificate
active
07351826
ABSTRACT:
The invention provides compounds of Formula (I) that bind to GABAAreceptors. In the above formula, variables are defined herein. Such compounds may be used to modulate ligand binding to GABAAreceptors in vivo or in vitro, and are particularly useful in the treatment of a variety of central nervous system (CNS) disorders in humans, domesticated companion animals, and livestock animals. Compounds provided herein may be administered alone or in combination with one or more other CNS agents to potentiate the effects of the other CNS agent(s). Pharmaceutical compositions and methods for treating such disorders are provided, as are methods for using such ligands for detecting GABAAreceptors (e.g., receptor localization studies)
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Han Bingsong
Xie Linghong
Xu Yuelian
Fidel Seth
Kadlecek Ann
Neurogen Corporation
Richter Johann R.
Schlientz Nathan W.
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