Artificial T helper cell epitopes as immune stimulators for synt

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 25 or more amino acid residues in defined sequence

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

530313, 530326, 4241981, A61K 3800, A61K 3824, A61K 3900

Patent

active

060254688

ABSTRACT:
The present invention is directed to novel peptide immunogens for eliciting antibodies to LHRH comprising artificial T helper cell epitopes (Th epitopes) designed to provide optimum immunogenicity. The artificial Th epitopes are covalently linked to LHRH and optionally an immunostimulatory seqence.

REFERENCES:
patent: 5023077 (1991-06-01), Gevas et al.
patent: 5759551 (1998-06-01), Ladd et al.
Babbitt et al., (1985) Nature, 317:359-361.
Bonneau et al., (1994) J. Anim. Sci., 72:14-20.
Borras-Cuesta et al., (1987) Eur. J. Immunol. 17:1213-1215.
Cease et al., (1987) Proc. Natl. Acad. Sci. 84:4249-4253.
Cornette et al., (1989) Methods in Enzymology 178:611-634.
Ennis et al., (1993) J. Exp. Med. 177:207-212.
Ferrari et al., (1991) J. Clin. Invest. 88:214-222.
Greenstein et al., (1992) J. Immunol. 148 (12):3970-3977.
Meister et al., (1995) Vaccine 13 (6):581-591.
Partidos et al., (1991) J. Gen. Virology 71:1293-1299.
Rothbard et al., (1988) EMBO Journal 7 (1):93-100.
Rudensky et al., (1991) Nature 353:622-627.
Sinigaglia et al., (1995) Immunol. Recogn. of Peptides in Medicine and Biology chap. 6:79-87.
Schutze et al., (1985) J. Immunol. 135 (4):2319-2322.
Stagg et al., (1993) Immunol. 79:1-9.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Artificial T helper cell epitopes as immune stimulators for synt does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Artificial T helper cell epitopes as immune stimulators for synt, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Artificial T helper cell epitopes as immune stimulators for synt will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1906946

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.