Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert
Reexamination Certificate
2006-02-21
2006-02-21
Lankford, Jr., Leon B. (Department: 1651)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Implant or insert
C623S004100, C623S006630, C623S024000, C623S025000, C623S026000, C435S325000, C435S395000, C424S422000
Reexamination Certificate
active
07001608
ABSTRACT:
The invention provides microfabricated devices and methods for directing the growth of a cell process to form an artificial synapse. The devices are called artificial synapse chips. The artificial synapse comprises a nanofabricated aperture (about 50–100 nm in size) that connects the cell process to a chemical or electrical means of neuronal excitation. Such an aperture width mimics the length scales of a natural synapse and thus emphasizes the localized spatial relationship between a neuron and a stimulation source. The invention further provides devices and methods for regenerating a nerve fiber into an electrode. The invention thus provides a regeneration electrode that uses a novel neural interface for stimulation and that uses novel surface methods for directing neuronal growth making possible in vivo connection of the devices to neural circuitry in a retina and other anatomical locations.
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Bent Stacey F.
Bloom David M.
Blumenkranz Mark
Fishman Harvey A.
Peterman Mark C.
Ford Allison M.
Lankford , Jr. Leon B.
Lumen Intellectual Property Services Inc.
The Board of Trustees of the Lealand Stanford Junior University
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