Artificial redox enzymes

Details Artificial redox enzymes Artificial redox enzymes

1991-04-04

1993-11-02

Griffin, Ronald W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

435183, 435188, 536 46, 536103, A61K 31715, A61K 3748, C08B 3018, C08B 3716

Patent

active

052583708

ABSTRACT:
Artificial redox enzymes are disclosed wherein one or more redox coenzymes or cofactors are linked to the 2-O, 3-O or 6-O positions of a D-glucopyranose ring of .alpha.-, .beta.-, or .gamma.-cyclodextrins. Also disclosed are facile synthetic methods for producing said artificial redox enzymes in good yield, and methods of use of such compositions.

REFERENCES:
patent: 3974274 (1976-08-01), Kurita et al.
patent: 4592996 (1986-06-01), Yamanishi et al.
patent: 4777250 (1988-10-01), Bender et al.
patent: 4834985 (1989-05-01), Elger et al.
patent: 5110833 (1992-05-01), Mosbach
J. Am. Chem. Soc., (1986), vol. 108, pp. 839-841 Cram et al.
Tabushi et al., J. Am. Chem. Soc. (1987) vol. 109, pp. 4734-4735.
Patent Abstracts of Japan, vol. 7, No. 213 (C-187) Sep. 20, 1983.
Hilvert et al., Bioorganic Chemistry, vol. 12, pp. 206-220 (1984).
Rong et al., Tetrahedron Letters, vol. 31, No. 30, Jul. 16, 1990, pp. 4275-4278.
Breslow, R., et al., J. Am. Chem. Soc., 100:3225-6 (1978).
D'Souza, V. T., et al., Biochem. Biophys. Res. Commun., 129:727-732 (1985).
Rao, K. R., et al., J. Chem. Soc. Chem. Commun., 0(1):10-11 (1990).
Breslow, R., et al., J. Am. Chem. Soc., 105:1390-1391 (1983).
Breslow, R., et al., Tetrahedron, 44:5515-5524 (1988).
D'Souza, V. T., et al., Acc. Chem. Res., 20:146-162 (1987).
Breslow, R., Cold Spring Harbor Symposia on Quantitative Biology, 52:75-81 (1987).
Breslow, R., Science, 218:532-537 (1982).
Royer, G. P., "Synthetic Enzyme Analogs (Synzymes)", Biotechnol., Ser. 5:297 (1985).
Breslow, R., Ann. N.Y. Acad. Sci., 471:60-69 (1986).
Breslow, R., "Artificial Enzymes and Enzyme Models", Adv. Enzymol. Relat. Areas Mol. Biol., 58:1-60 (1986).

Affiliated with

Also associated with

Rating

Artificial redox enzymes does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Artificial redox enzymes, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Artificial redox enzymes will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1757543