Artificial peptides having surface activity and the use...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Reexamination Certificate

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C514S013800, C530S326000

Reexamination Certificate

active

07053044

ABSTRACT:
SP-C analogue artificial peptides having surface activity are disclosed and their use for preparing artificial surfactants useful in the treatment of respiratory distress syndrome (RDS) and other diseases related to surfactant deficiency or dysfunction.

REFERENCES:
patent: 0 368 823 (1990-05-01), None
patent: 0 733 645 (1996-09-01), None
patent: WO 91/18015 (1991-11-01), None
Palmblad et al. “Biophysical activity of an artifical surfactant containing an analogue of surfactant protein (SP)-C and native SP B” 1999, Biochem J. 339(2) pp 381-386.
Marie Palamblad, et al., Biophysical activity of an artificial surfactant containing an analogue of surfactant protein (SP)-C and native SP-B, Biochemical Journal, vol. 339, pp. 381-386, 1999.
Tsunetomo Takei, et al., The Surface Properties of Chemically Synthesized Peptides Analogous to Human Pulmonary Surfactant Protein SP-C, Biol. Pharm. Bull. vol. 19, pp. 1247-1253, 1996.
U.S. Appl. No. 10/512,869, filed Nov. 16, 2004, Curstedt, et al.
U.S. Appl. No. 09/926,009, filed Oct. 3, 2001, Curstedt, et al.

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