Artificial pancreatic perfusion device

Details Artificial pancreatic perfusion device Artificial pancreatic perfusion device

1989-08-25

1991-03-26

Jones, W. Gary

Liquid purification or separation

With preliminary chemical manufacture

210209, 21032178, 21032187, 424424, 435284, 604 4, 604175, B01D 6306

Patent

active

050026615

ABSTRACT:
A device which serves as an artificial pancreas comprises a hollow fiber having an inner diameter of about 5 mm which is surrounded by islets of Langerhans enclosed in a housing. The islets are suspended in a semi-solid matrix which ensures desired distribution of the cells about the hollow fiber. The hollow fiber and suspended islets are enclosed in a housing which further aids the desired distribution of islets about the hollow fiber. The hollow fiber has a porosity which selectively allows passage of substances having a molecular weight of less than about 100,000 Daltons. The semi-solid matrix in which the islets are embedded and suspended is formed of an appropriate supporting material such as alginate or agar.

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