Artificial oxygen carrier and production method thereof

Details Artificial oxygen carrier and production method thereof Artificial oxygen carrier and production method thereof

2007-10-23

2007-10-23

Mondesi, Robert B. (Department: 1652)

Chemistry: molecular biology and microbiology

Maintaining blood or sperm in a physiologically active state...

C435S069600, C530S350000

Reexamination Certificate

active

10927675

ABSTRACT:
The present invention provides a method of producing a complex of albumin and a deoxy form metal complex having a porphyrin structure, which includes mixing albumin and a metal complex having a porphyrin structure under a gas atmosphere substantially free of carbon monoxide and oxygen, as a method of producing an artificial oxygen carrier containing a complex of albumin and a metal complex having a porphyrin structure, under a deoxidation (nitrogen, other inert gases) atmosphere without using carbon monoxide.

REFERENCES:
patent: 5773417 (1998-06-01), Bonaventura
patent: 6008198 (1999-12-01), Tsuchida et al.
patent: 08-301873 (1996-11-01), None
patent: 10-503489 (1998-03-01), None
patent: 2001-072595 (2001-03-01), None
Sue Parham, published on the web at www.aabb.org/Content/Meetings—and—Events/Annual—Meeting—and—TXPO/58amtueoxy.htm, Jan. 2006, pp. 1-2.
Komatsu et al.,Artificial Blood, 6(4): 110-114 (1998).
Tsuchida et al.,Bioconjugate Chem., 8(4): 534-538 (1997).
Tsuchida et al.,Bioconjugate Chem., 10(5): 797-802 (1999).

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