Artificial chromosome

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Transferase other than ribonuclease

Reexamination Certificate

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C435S254200, C435S254210, C435S069100, C536S023100, C530S370000, C530S387300, C530S388210

Reexamination Certificate

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06905860

ABSTRACT:
An artificial mammalian chromosome, more specifically, a clone containing a mammalian centromere sequence and a DNA replication origin with mammalian telomere sequences added to both ends of the clone, is provided by preparing a CEPH artificial yeast chromosome library containing a human genome, identifying clones having a repetitive human alphoid sequence from this library, and further preparing a yeast strain in which mammalian telomere sequences are added to the ends of its chromosome.

REFERENCES:
patent: 2263823 (1998-03-01), None
patent: WO 98/08964 (1998-03-01), None
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