Artificial cartilage tissue and production method thereof

Details Artificial cartilage tissue and production method thereof Artificial cartilage tissue and production method thereof

2011-04-12

2011-04-12

Desai, Anand U (Department: 1656)

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

Primate cell, per se

C424S093700

Reexamination Certificate

active

07923244

ABSTRACT:
To obtain an artificial cartilage tissue having high strength and biocompatibility. There is provided an artificial cartilage tissue which is substantially free of heterologous protein and is substantially free of scaffold derived from non-cartilage-derived cells, but contains mammalian cartilage-derived cells and an extracellular matrix formed by the cartilage-derived cells, where: (1) the water retention per mg of tissue dry weight is 17.8 mg or less; (2) collagen of 5.57 μg or more per mg of tissue wet weight is contained; (3) proteoglycan of 9.22 μg or more per mg of tissue wet weight is contained.

REFERENCES:
patent: 5326357 (1994-07-01), Kandel
patent: 5786217 (1998-07-01), Tubo et al.
patent: 6197061 (2001-03-01), Masuda et al.
patent: 6451060 (2002-09-01), Masuda et al.
patent: 6676969 (2004-01-01), Geistlich et al.
patent: 6730314 (2004-05-01), Jeschke et al.
patent: 2002/0052044 (2002-05-01), Jeschke et al.
patent: 2003/0153078 (2003-08-01), Libera et al.
patent: 2001-224678 (2001-08-01), None
patent: 2003-304866 (2003-10-01), None
patent: WO 00/17321 (2000-03-01), None
patent: WO 00/51527 (2000-09-01), None
patent: WO 01/60424 (2001-08-01), None
Brittberg, M. et al., “Treatment of deep cartilage defects in the knee with autologous chondrocyte transplantation”, N Engl J Med 331: 889-895 (Oct. 1994).
Brittberg et al., “Treatment of Deep Cartilage Defects in the Knee with Autologous Chondrocyte Transplantation”, The New English Journal of Medicine, vol. 331, No. 14, Oct. 6, 1994, pp. 889-895.
Rodriguez et al., “Characteristics of Cartilage Engineered from Human Pediatric Auricular Cartilage”, Plastic and Reconstructive Surgery, vol. 103, No. 4, Apr. 1999, pp. 1111-1119.
Merrihew et al., “The Effect of Human Serum in the Production of Engineered Human Cartilage Constructs Using the Alginate-Recovered Chondrocyte Method”, Paper No. 0821, 52ndAnnual Meeting of the Orthopaedic Research Society, 2006.
Masuda et al., “A novel two-step method for the formation of tissue-engineered cartilage by mature bovine chondrocytes: the alginate-recovered-chondrocyte (ARC) method”, Journal of Orthopaedic Research, vol. 21, 2003, pp. 139-148.
Stoddart et al., “Generation of a scaffold free cartilage-like implant from a small amount of starting material”, J. Cell. Mol. Med., vol. 10, No. 2, 2006, pp. 480-492.
Masuda et al., “Tissue-engineered Human Articular Cartilage produced from Knee Biopsy Specimens-Alginate-recovered-chondrocyte Method and Osteogenic Protein-1”, Paper No. 6202, ICRS, 2002.
Matsuzaka et al., “Formation of Cartilaginous Tissue by the Alginate-Recovered-Chondrocyte Method and in vivo Transplantation to Full-Thickness Defects in Swine Articular Cartilage-Feasibility Study”, Paper No. 0453, 48thAnnual Meeting of the Orthopaedic Research Society, 2002.
Chen et al., “Tissue Engineered Cartilage From Adult Human Chondrocytes: Biomechanical Properties and Function-Composition Relationships”, Paper No. 945, 49thAnnual Meeting of the Orthopaedic Research Society, 2003.
Yanaga, Hiroko, et al., excerpt from “Microtia Operation Using Autologous Cultured Cartilage”, The 48thAnnual Meeting of Japan Society of Plastic and Reconstructive Surgery, p. 196, No. 088, Mar. 18, 2005.

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