Artificial cardiopulmonary circuit system

Chemical apparatus and process disinfecting – deodorizing – preser – Blood treating device for transfusible blood – Oxygenator

Reexamination Certificate

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Details

C604S006140, C210S500350, C210S500230, C210S490000

Reexamination Certificate

active

06994824

ABSTRACT:
To provide an artificial cardiopulmonary circuit system having high heat resistance and excellent blood compatibility. The artificial cardiopulmonary circuit system includes a hollow fiber membrane oxygenator including a plurality of porous hollow fiber membranes for gas exchange having a blood contact part that contacts blood on one side thereof and a gas contact part that contacts a gas on the other side thereof, and a housing that contains the hollow fiber membranes therein. At least a portion of the blood contact part of the hollow fiber membrane oxygenator is coated with a polymer comprising a repeating unit represented by the following general formula (1) as a main structural component and having a viscosity at 65° C. of 5,000 poise (500 Pa·s)[Chemical Formula 4](Wherein R1is hydrogen or a methyl group, R2is an alkylene group having 1 to 4 carbon atoms, and R3is an alkyl group having 1 to 4 carbon atoms).

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T. Matsuda et al., “Complement Activaton on Polymer Surfaces and Its Effector Function to Immunocompetent Cells”,Jpn. J. Artificial Organs, 16(2), pp. 1045-1050 (1987).

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