Artificial blood vessel and process for producing the same

Prosthesis (i.e. – artificial body members) – parts thereof – or ai – Arterial prosthesis – Stent structure

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623 12, 600 36, A61F 206, A61F 204

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057187231

ABSTRACT:
This invention provides a more functionalized artificial blood vessel which can be organized by independently designing its inner and outer surfaces and endowing them with respectively different biocompatibilities, as well as a process for producing the same.
The artificial blood vessel comprises a tubular support having a layer of photogelled cinnamic acid-bound chondroitin sulfate coated on the inner surface thereof and a layer of photogelled coumarin-bound gelatin coated on the outer surface thereof. The process for producing the above artificial blood vessel comprises coating a layer of coumarin-bound gelatin on the outer surface of a tubular support and a layer of cinnamic acid-bound chondroitin sulfate on the inner surface of the support and irradiating each of the layers with light.

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Shimomura et al., "Photochemical Reaction of Stilbazole Amphiphile in Cast Orientated Film," The Chemical Society of Japan, 10:1185-1188 (1990).
The Japanese Society of Gastroenterological Surgery, The Japanese Journal of Gastroenterological Surgery, vol. 25, No. 6, 1992, p. 1509.

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