Articles having graft polymer bioactive surfaces

Prosthesis (i.e. – artificial body members) – parts thereof – or ai – Arterial prosthesis – Stent structure

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623 11, 606 76, 604266, A61F 206

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active

054765099

ABSTRACT:
Articles comprised of bioactive agents coupled to or repelled by a graft polymer (made, for example, from monomers such as N-(3-aminopropyl) methacrylamide hydrochloride (APMA), 2-acrylamido-2-methylpropane sulfonic acid (AMPS), acrylamide (AAm), and acrylic acid (AA)) which is in turn bonded to a polymeric substrate surface. The articles are useful as thromboresistant and/or antimicrobial medical devices.

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Cell Behavior on Polymer Surfaces Grafted with Non-ionic and Ionic Monomers, by Akio Kishida et al., Biomaterials, 1991, vol. 12, Oct.
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