Article having biocompatible surface

Details Article having biocompatible surface Article having biocompatible surface

1991-11-12

1993-07-20

Prescott, Arthur C.

Coating processes

Medical or dental purpose product; parts; subcombinations;...

Particulate or unit-dosage-article base

128912, 428 357, 558166, 525937, A01N 102, B01J 1600, B29C 7100, B29D 2200

Patent

active

052291626

ABSTRACT:
A compound of formula: ##STR1## in which X.sup.1 is a reactive group that can react to form a covalent bond with a reactive group on the surface of a material to be rendered biocompatible, X.sup.2 is a group -O.sup..crclbar. or a precursor of such a group, n is 2, 3 or 4, Y is a group --N.sup..sym. R.sub.3 A.sup..crclbar. wherein each R, which may be the same or different, is a C.sub.1 -C.sub.4 alkyl group and A.sup..crclbar. is an anion present when X.sup.2 is an electrically neutral group or Y is ##STR2## wherein R.sup.1 together with X.sup.2 forms a direct bond between the nitrogen and the phosphorus atoms.

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Kosolapoff et al., "Organic Phosphorus Compds.", vol. 6, p. 227, (1974).
Kodaira et al., Jrnl. of Organ. Chem., vol. 33, pp. 2903-2907, (1966).
Journal of Organic Chemistry, vol. 31, pp. 2903-2907 (1966) Y. Kodaira and T. Mukaiyama.
Organic Phosphorus Compounds, vol. 6, John Wiley & Sons, New York, 1974; G. M. Kosolapoff and L. Maier.

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