Article for culturing differentiated cells

Details Article for culturing differentiated cells Article for culturing differentiated cells

1982-06-25

1985-02-26

Kepplinger, Esther M.

Chemistry: molecular biology and microbiology

Apparatus

Differentiated tissue perfusion or preservation apparatus

435285, 435273, 260112R, C12M 300, C12M 304

Patent

active

045018154

ABSTRACT:
A method, solid-state culture support and culture solution are disclosed which enables successful in vitro culturing of differentiated cells, with significant retention of their differentiated character. Through the use of extracellular matrix fibers, specifically derived from connective tissue, as culture substrates, the method also discloses the isolation of the connective tissue fibers and their preparation as a culture substrate. This method provides significantly higher survival and attachment rates, and often significantly improved growth properties for in vitro cultures of differentiated cells, especially epithelial, over the current methods for culturing these cells.
This method also significantly enables certain differentiated cells to retain much of their normal enzymatic activities.
Furthermore, this method enables certain differentiated cells to retain to a high degree, their ability to secrete substances, such as hormones.

REFERENCES:
Meezan et al., Life Sciences, 17: 1721-1732.

Affiliated with

Also associated with

Rating

Article for culturing differentiated cells does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Article for culturing differentiated cells, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Article for culturing differentiated cells will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-516984