Article comprising a dispensing container that includes solid po

Details Article comprising a dispensing container that includes solid po Article comprising a dispensing container that includes solid po

1990-04-06

1992-12-01

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Dentifrices

424 52, 424 57, 514900, 514901, 2065241, 2065243, A61K 716, A61K 718

Patent

active

051679515

ABSTRACT:
An oral composition, such as a paste or gel dentifrice or a liquid mouthwash, containing a substantially water insoluble non-cationic antibacterial agent, such as triclosan, which, when used to clean the teeth or rinse the mouth, acts to decrease plaque on the teeth, is packaged in a dispensing container which includes a solid polymeric material, such as polyfluoroethylene, which is compatible with the antibacterial agent so that excessive loss of anti-plaque activity of such agent on storage is avoided. Alternatively, various other polymers may be employed as container parts, which normally would cause excessive losses of anti-plaque action of the antibacterial agent in the composition, but such action is countered by the presence of a stabilizer, such as a terpene, e.g., limonene, in the oral composition formula. The oral composition preferably contains a tooth hardening proportion of a source of fluoride ions, an anti-tartar proportion of a polyphosphate, a stabilizing proportion (in conjunction with the fluoride source) for the polyphosphate, of a polyvinyl methyl ether-maleic anhydride copolymer, and normal adjuvants for the oral preparation. A method for inhibiting development of plaque on teeth is also within the invention, as is a cleaning article containing an effective amount of the invented dentifrice.

REFERENCES:
patent: 3956480 (1976-05-01), Dichter et al.
patent: 4022880 (1977-05-01), Vinson et al.
patent: 4510127 (1985-04-01), Chang
patent: 4515772 (1985-05-01), Parran, Jr. et al.
patent: 4595613 (1986-06-01), Tavss et al.
patent: 4627977 (1986-12-01), Gaffar et al.
patent: 4716034 (1987-12-01), Schelm
patent: 4830221 (1989-05-01), Mazzanobile

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