Drug – bio-affecting and body treating compositions – Dentifrices
Patent
1989-10-26
1992-08-04
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Dentifrices
424 52, 424 57, 424 58, 206277, 2065241, 2065243, 222107, 514718, 514721, 514900, 514901, 514902, A61K 716
Patent
active
051357380
ABSTRACT:
An oral composition, such as a paste or gel dentifrice or a liquid mouthwash, containing a substantially water insoluble non-cationic antibacterial agent, such as triclosan, which, when used to clean the teeth or rinse the mouth, acts to decrease plaque on the teeth, is packaged in a dispensing container or bottle which includes a solid polymeric material, such as polyfluoroethylene, which is compatible with the antibacterial agent so that excessive loss of anti-plaque acitivity of such agent on storage is avoided. Alternatively, various other polymers may be employed as container parts, which normally would cause excessive losses of anti-plaque action of the antibacterial agent in the composition but such action is countered by the presence of a stabilizer, such as a terpene, e.g., limonene, in the oral composition formula. Also described is a method for inhibiting development of plaque on teeth.
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patent: 4830221 (1989-05-01), Mazzanobile
Collins Michael A.
Gaffar Abdul
Miller Jeffrey
Potini Chimpiramma
Robinson Richard S.
Colgate-Palmolive Company
Grill Murray M.
Page Thurman K.
Spear James M.
Stone Robert L.
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