Arthropod repellent pharmacophore models, compounds...

Details Arthropod repellent pharmacophore models, compounds... Arthropod repellent pharmacophore models, compounds...

2011-03-01

2011-03-01

Levy, Neil (Department: 1615)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Biocides; animal or insect repellents or attractants

C424S047000, C424S059000, C424S403000, C424S412000, C424S413000, C424S414000, C424S415000, C424S416000, C514S622000, C514S678000, C514S919000

Reexamination Certificate

active

07897162

ABSTRACT:
Disclosed herein is a pharmacophore model for arthropod repellent activity and methods of making and using thereof. The pharmacophore comprises two hydrophobic aliphatic functions, one aromatic function and one hydrogen bond acceptor function. The pharmacophore model was made using a test set of arthropod repellent compounds. Also disclosed are arthropod repellent compounds identified by screening databases with the pharmacophore model. Also disclosed are methods of repelling arthropods from a surface or area. Compositions and formulations comprising the compounds of the present invention as well as objects having the compounds of the present invention are disclosed.

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