Arthrobacter strain producing esterase for the enantioselective

Details Arthrobacter strain producing esterase for the enantioselective Arthrobacter strain producing esterase for the enantioselective

1995-05-31

1997-04-22

Marx, Irene

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

435830, C12N 120

Patent

active

056228589

ABSTRACT:
The invention concerns a microbial esterase which enantioselectively cleaves (S)-1-phenylethyl acetate and is obtainable from Arthrobacter spec. (DSM 7034), Pseudomonas fluorescens (DSM 7033) or Bacillus subtilis (DSM 7035) as well as a process for enantioselectively cleaving a 1-arylalkyl ester of a carboxylic acid and a process for the production of an enantiomerically-pure 1-arylalkanol using this esterase.

REFERENCES:
Cambou et al., J. Am. Chem. Soc., 1984, 106, 2687-2692.
Whitesell et al., CHIMIA, 40, 9 (Sep.), 1986.
Santaniello et al., Gazzetta Chimica Italiana, 119, 1989, 581-584.
Laumen et al., Chem. Soc. Chem. Commun., 1988, 1459-1461.
Janssen et al., Tetrahedron, vol. 47, No. 36, 7645-7662, 1991.
Mori et al., Tetrahedron, vol. 36, 91-96, 1980.
Oritani et al., Agri. Biol. Chem. 37 (8), 1923-1928, 1973.
Danda et al., Tetrahedron, 47 (41), 8701-8716, 1991.

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