Arterial wall cholesterol ester reducing cyclopropanyl-bearing a

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...

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26032614T, 26032647, 260404, 260413, 424274, 564188, 564190, A61K 31165, A61K 3140, C07C10320, C07C10337

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active

042488931

ABSTRACT:
Cyclopropanyl-group-bearing-amides, eg N-[1-(benzyl)-2-(phenyl)ethyl]-cis-2-octyl-cyclopropanoctanamide and N-(.alpha.-methyl-benzyl)-(cis)-2-octyl-cyclopropanoctanamide, are useful as pharmaceutical agents and are obtainable, eg by reacting a mixed anhydride of a cyclopropanyl-group bearing-long chain carboxylic acid with an appropriate amino compound.

REFERENCES:
patent: 2811532 (1957-10-01), Riedman
patent: 3621043 (1971-11-01), Seki
patent: 3741999 (1973-07-01), Seki
patent: 3995059 (1976-11-01), Fukumaru
Fieser & Fieser, Advanced Organic Chem. (1961) p. 549.

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