Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1997-07-03
1999-01-05
Stockton, Laura L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
A61K 31335
Patent
active
058563512
ABSTRACT:
Novel artemisinin dimers of structure ##STR1## which possess anticancer activity.
REFERENCES:
patent: 5225437 (1993-07-01), Posner et al.
"Synthesis of a Novel Ring Contracted Artemisinin Derivative," Bioorganic & Medicinal Chemistry Letters 4(5)751-752 (1994).
"Qinghaosu (Artemisinin): An Antimalarial Drug from China,", D.L. Klayman, Science 228:1049-1055 (May 1985).
"Cytotoxicity of Artemisinin-Related Endoperoxides to Ehrlich Ascites Tumor Cells," Journal of Natural Products, 56(6): 849-856 (Jun. 1993).
"Artemisinin (Qinghaosu): A New Type of Antimalarial Drug," Department of Chemistry, University of St. Andrews, Scotland, Anthony R. Butler.; Chemical Society Reviews (1992), pp. 85-90.
"Exradorinarily Potent Antimalarial Compounds: New, Structurally Simple, Easily Synthesized, Tricyclic 1,2,4-Trioxanes," Journal of Medicinal Chemistry vol. 35, No. 13, (1992).
"Artemisinin," The Royal Society of Tropical Medicine and Hygiene, vol. 88 Supplement 1 (Jun. 1994).
Screening Date Summary NSC 369397, National Cancer Institute Report, Jan. 5, 1995.
Darbie Lynn G.
Zheng Qun Y.
Petersen Steven C.
Stockton Laura L.
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