Arsenic-72 labeled compounds for tissue specific medical imaging

Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing

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424 111, 424 165, 424 181, 424 169, A61K 4900, G01N 3100, G01N 3348

Patent

active

061068047

ABSTRACT:
Radioactive arsenic (.sup.72 As) labelled tissue specific ligands are prepared and used in the medical imaging of malignant breast or prostate tumors.

REFERENCES:
patent: 5169933 (1992-12-01), Anderson et al.
patent: 5443816 (1995-08-01), Zamora et al.
patent: 5460785 (1995-10-01), Rhodes et al.
Hembrough, T.A; Li, L; Gonias, S.L; Cell-Surface Cytokeratin-8 is the Major Plasminogen Receptor on Breast Cancer cels and is Required for the Accelerated Activation of Cell-Associated Plasminogen by Tissue-Type Plasminogen Activator. J. Biol Chem (1996); 271(41):25684-25691.
Palmer, R.B; Upthagrove, A. L; Nelson, W.L;(E)- nd (Z)-7-Arylidenenaltrexones: Synthesis and Radioligand Displacement Assays. J Med Chem (1997); 40(5):749-753.
Fortunati, N; Fissore, F; Fazzari, A; Becchis, M; Comba, A; Catalano, M.G; Berta, L; Frairia, R; Sex-Steriod Binding Protein Exerts Negative Control on Estradiol Action in MCF-7 Cells (Human Breast Cancer) Through Cyclic Adenosin 3',5'-Monophosphate and Protein Kinase A. Endocrinology (1996); 137(2):686-692.
Williams, C.L; Stancel, G.M; Estrogens and Progestins. In, Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th Ed., J.G. Hardman and L.E. Limbird (Eds.), McGraw-Hill: New York, (1996); 1423-1440.
Banerjee, R; Ginsburg, E; Vonderhaar, B.K; Characterization of a Monoclonal Antibody Against Human Prolactin Receptors. Int J ancer (1993); 55(5):712-721.
Reubi, J.C; In Vitro Identification of Vasoactive Intestinal Receptors in Human Tumors: Implications for Tumor Imaging. J Nucl Med (1995); 36(10):1846-1853.
Fritta, L; Vigneri, R; Papa, V; Goldfine, I.D; Grasso, D; Trischitta, V; Structural and Functional Studies of Insulin Receptors in Human Breast Cancer Res Treat (1993); 25(1):73-82.
Formento, J.L; Francoual, M; Formento, P; Eitenne, M.C; Fischel, J; Namer, M; Frenay, M; Francois, E; Milano, G; Epidermal Growth Factor Receptor Assay: Validation of a Single Point Method and Application to Breast Cancer. Breast Cancer Res Treat (1991); 17(3):211-219.
N. Touchette, Breast Cancer: Roulette or Calculated Risk;, J. NIH Research, Oct., 33, (1993).
D.P. Swanson, J.M. Chilton and J.H. Thrall, Pharmaceuticals in Medical Imaging, MacMillan Publishing Company: New York, v-viii, (1990).
S. Jurrison, D. Berning, W. Jia and D. Ma, Chem. Rev., 93, 1137, (1993).
A.-C. Chang, C.C. Chaoo, A.E. Takemori, G. Gekker, S. Hu, P.K. Peterson and P.S. Portoghese, J. Med. Chem., 39, 1729, (1996).
J.B. Arterburn, I.M. Fogarty, K.A. Hall, K.C. Ott and J.C. Bryan, Functionalized Organoimidorhenium (V) Complexes as Potential Radiopharmaceuticals: Syntheses of Glycine Derivatives and the Structure Determination of a Rhenium Analogue of Chlorambucil. Angew. Chem. Int. Ed. Engl., 35, 2877, (1996).
A.J. Gordon and R.A. Ford, The Chemist's Companion: A Handbook of Practical Data, Techniques and References. John Wiley and Sons: New York, NY, 83, (1972).
E.P. Adams, F.P. Doyle, W.H. Hunter and J.H.C. Nayler, J. Chem. Soc., 2674, (1960).
P.J.E. Brownlee, M.E. Cox, B.O. Handford, J.C. Marsden and G.T. Young, Jr. Chem. Soc., 3832, (1964).
R.W. Bruggenmeier, D.D. Miller and D.T. Witiak, Cholesteol, Adrenocorticoids and Sex Hormones. In, Principles of Medicinal Chemistryl, 4th ed., W.O. Foye, T.L. Lemke and D.A. Williams (Eds.), Williams and Wilkins: Media, PA, 444-498, (1995).

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