Arrays of modified nucleic acid probes and methods of use

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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422 50, 422 681, 4352831, 4352871, 4352872, 4352883, 4352887, 4352891, 4352991, 4353051, 436501, 536 221, 536 241, 536 243, 536 2431, 536 2432, 536 2433, C12Q 168, C07H 2100

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061565016

ABSTRACT:
Oligonucleotide analogue arrays attached to solid substrates and methods related to the use thereof are provided. The oligonucleotide analogues hybridize to nucleic acids with either higher or lower specificity than corresponding unmodified oligonucleotides. Target nucleic acids which comprise nucleotide analogues are bound to oligonucleotide and oligonucleotide analogue arrays.

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