Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1995-06-06
1998-04-28
Zitomer, Stephanie W.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 792, 435 794, 435 795, 435969, 435973, 436518, 436527, 436807, 436809, 530334, 536 243, 536 253, 536 2532, C12Q 168, C07H 2104, C07H 2102
Patent
active
057443050
ABSTRACT:
A synthetic strategy for the creation of large scale chemical diversity. Solid-phase chemistry, photolabile protecting groups, and photolithography are used to achieve light-directed spatially-addressable parallel chemical synthesis. Binary masking techniques are utilized in one embodiment. A reactor system, photoremovable protective groups, and improved data collection and handling techniques are also disclosed. A technique for screening linker molecules is also provided.
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Fodor Stephen P.A.
Pirrung Michael C.
Read J. Leighton
Stryer Lubert
Affymetrix Inc.
DeSantis Nancy J.
Liebeschuetz Joseph
Norviel Vern
Tran Paul B.
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