Array imaging method

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

Reexamination Certificate

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Details

C435S174000, C435S283100, C435S287200, C422S068100, C422S082050, C422S082080, C536S023100, C536S024300, C530S300000, C530S358000

Reexamination Certificate

active

06897026

ABSTRACT:
A method for imaging molecules contained in an array of discrete reaction sites on the surface of a solid support comprises:(i) imaging the array and detecting a first molecule located on the solid support at a known position with respect to the array;(ii) by reference to the first molecule, aligning inspection windows in registration with the discrete reaction sites; and(iii) determining the amount of detectable signal in each window.The method is used to locate the reaction sites accurately on the array, and to correct for any misalignments.

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