Arrangement and method for performing chromatography

Liquid purification or separation – Processes – Chromatography

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C210S748080, C210S198300, C210S243000, C204S450000

Reexamination Certificate

active

10646125

ABSTRACT:
An arrangement for performing chromatography with a mobile phase and a chromatographic bed having a stationary phase is provided. The arrangement includes a support assembly configured to support the stationary phase. The support assembly has a sealed cavity configured so that when the support assembly is supporting the stationary phase a portion of the chromatographic bed and the stationary phase extends into the sealed cavity. The arrangement further includes a bladder having a void defined therein. The bladder is positioned within the sealed cavity. The arrangement also includes a fluid positioned within the void of the bladder so that the bladder is urged toward the stationary phase within the sealed cavity. The arrangement further includes an anode positioned in contact with the mobile phase. The arrangement also includes a cathode positioned in contact with the stationary phase, wherein creating an electrical potential between the anode and the cathode causes the mobile phase to be advanced through the chromatographic bed positioned within the sealed cavity. An associated method is also provided.

REFERENCES:
patent: 3864250 (1975-02-01), Perry
patent: 4346001 (1982-08-01), Tyihak
patent: 4438205 (1984-03-01), Saint Leger
patent: 4591524 (1986-05-01), Tyihak
patent: 4671870 (1987-06-01), Tompa
patent: 4671871 (1987-06-01), Szekely
patent: 4708782 (1987-11-01), Andersen
patent: 4740298 (1988-04-01), Andersen
patent: 4865729 (1989-09-01), Saxena
patent: 5248426 (1993-09-01), Stillian et al.
patent: 5350510 (1994-09-01), Partney
Two Records from Dialog regarding Nurok (Journal of Planar Chromatography, vol. 11, Jul./Aug. 1998, pp. 244-246), two pages.
Conference Report; Journal of Planar Chromatography, 1993; 355-356; Authored by Ian Davies.
Electroosmotically driven thin-layer electrochromatography on silica media; 1999; J. Chromatogr. 844; 333-340; Authored by Howard et al.
Evaporation-induced solvent migration in electrically-driven thin layer chromatography; 1999, J. Chromatogr. 841; 127-132; Authored by Shafik et al.
Electro-osmosis: A new concept for high-speed liquid chromatography; Journal of Chromatography; 1974; 99; 23-30; Authored by Pretorius et al.
Planar Electrochromatography on non-wetted thin-layers; Chromatographia; Jan. 1994; vol. 38, No. 1/2; 83-87; Authored by Pukl et al.
Planar Electrophoresis and Electrochromatography: Time to Revisit these Techniques?; Journal of Planar Chromatography; Sep./Oct. 97; vol. 10; 332-335; Authored by Poole et al.
Electrokinetic Ultrafiltration Analysis of Polysaccharides: A new Approach to the Chromatography of Large Molecules; International Congress on Analytical Chemistry; Jun. 3, 1952; 964-969; Authored by D. L. Mould and R. L. M. Synge.
Separations of Polysaccharides related to Starch by Electrokinetic Ultrafiltration in Collodin Membranes; The Rowett Research Institute, Bucksburn, Aberdeenshire; Apr. 15, 1954; 571-585; Authored by D. L. Mould and R. L. M. Synge.
D. Nurok et al., “The Performance of Planar Chromatography using Electroosmotic Flow”,Journal of Planar Chromatography, vol. 11, Jul./Aug. 1998, pp. 244-246.
D. Nurock et al., “Separation Using Planar Chromatography with Electroosmotic Flow”,Journal of Chromatography A, 903, 2000, pp. 211-217.
D. Nurock et al., “Variables that Affect Performance in Planar Chromatography with Electroosmotic Flow”,Journal of Planar Chromatography, vol. 14, Nov./Dec. 2001, pp. 409-414.
D. Nurock et al., “The Performance of Planar Electrochromatography in Horizontal Chamber”,Journal of Planar Chromatography, vol. 15, Sep./Oct. 2002, pp. 320-323.
D. Nurock et al., “Role of Buffer Concentration and Applied Voltage in Obtaining a Good Separation in Planar Electrochromatography”,Journal of Chromatrography A, 983, 2003, pp. 247-253.
T. H. Dzido et al., “Planar Electromatography in Horizontal Chamber with Cooling of the Chromatographic Plate”,Proc. International Symposium on Planar Separations, Budapest, 2003, pp. 129-138.
T. Dzido et al., “Application of a Horizontal DS Chamber to Planar Electrochromatography”,Journal of Planar Chromatography, vol. 16, May/Jun. 2003, pp. 176-182.
I. Malinowska et al., “Planar Electrochromatography on Silica and Alumina”,Journal of Planar Chromatography, vol. 11, Nov./Dec. 1998, pp. 411-416.
I. Malinowska, The Inlfuence of Electric Fields on the Chromatographic Process in TLC,Journal of Planar Chromatography, vol. 12, Nov./Dec. 1999, pp. 408-415.
I. Malinowska, “Planar Electrochromatogrphy on Nonwetted Layers with Binary Mobile Phases”,Journal of Planar Chromatography, vol. 13, Jul./Aug. 2000, pp. 307-313.
I. Malinowska, “Some Aspects of the Effect of an Electric Field in Reversed-Phase Thin-Layer Chromatography”,ACTA Chromatographica, No. 11, 2001, pp. 204-214.
I. Malinowska et al., “The Effect of Electric Fields on Solute Migration and Mixture Separation in TLC”,Journal of Planar Chromatography, vol. 15, Nov./Dec. 2002, pp. 418-424.
V. Coman et al., “Planar Dielectrochromatogrphy—A Perspective Technique”,Journal of Planar Chromatography, vol. 16, Sep./Oct. 2003, pp. 338-346.
S. Kreibik et al., “Horizontal Planar Dielectrochromatography. I. Preliminary Results”,Journal of Planar Chromatography, vol. 15, Nov./Dec. 2002, pp. 425-428.
J. K. Różlo et al., “10 Electroosmotically driven TLC—in Planar Chromatography: A Retrospective View for the Third Millennium, Nyiredy, SZ. ed.”,Springer Scientific, Budapest, Hungry, 2001, pp. 200-219.
R. Consden et al., “Ionophoresis in Silica Jelly—A Method for the Separation of Amino-Acids and Peptides”,Biochem. J., vol. 40, 1946, pp. 33-41.
D. Nurock et al., “Apparatus and Initial Results for Pressurized Planar Electrochromatography”,Analytical Chemistry, vol. 76, No. 6, Mar. 15, 2004, pp. 1690-1695.
J. M. Koers et al., “Performance of Planar Electrochromatography at Elevated Pressure”,Proc. International Symposium on Planar Separations, Budapest, 2003, pp. 123-128.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Arrangement and method for performing chromatography does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Arrangement and method for performing chromatography, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Arrangement and method for performing chromatography will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3832883

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.