Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1985-08-26
1987-04-28
Daus, Donald G.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
544332, A61K 31495, C07D23902
Patent
active
046614958
ABSTRACT:
New arphamenine-related compounds are now provided, which are represented by the formula ##STR1## wherein R.sub.1 denots a hydrogen atom or an amino-protecting group, R.sub.2 denotes a dimethylpyrimidinyl group, R.sub.3 denotes a hydrogen atom or a hydroxyl group, and R.sub.4 denotes a hydrogen atom or a carboxyl-protecting group. The new arphamenine-related compounds exhibit a carboxypeptidase-inhibitory activity and also an immunopotentiating activity and are useful for potentiating the immune response in a living animal.
REFERENCES:
Ohuchi et al., J. of Antibiot. 1984, 37(12) 1741-3.
Ohuchi et al, J. of Antibiot. 1983, 36(11) 1576-80.
Ohuchi et al, Chem. Abst. 100-175223k.
Ohuchi et al, Chem. Abst. 100-101620r.
Ohuchi et al, Chem. Abst. 102-74753u.
Aoyagi Takaaki
Ohuchi Shokichi
Takeuchi Tomio
Umezawa Hamao
Daus Donald G.
Shen Cecilia
Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai
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