Aromatic nitro and nitroso compounds and their metabolites usefu

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...

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564166, C07C23365, C07C20704, A61K 3124

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active

054648718

ABSTRACT:
Unsubstituted or substituted halo nitro and nitroso compounds and their metabolites are potent, selective and non-toxic inhibitors and supressants of cancer growth and viral infections in a mammalian host. The compounds are particularly useful for treatment and supression of tumors and viruses associated with breast cancer, AIDS, herpetic episodes and cytomegaloviral infections. The methods of treatment of tumorigenic and viral diseases by halo nitro nitroso compounds and their metabolites are described.

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patent: 2937204 (1960-05-01), Harris
patent: 3161564 (1964-12-01), Morehouse
patent: 3228833 (1966-01-01), Crounse
patent: 5283352 (1994-02-01), Backstrom
Hickman, John A., "Protection Against . . . ", Biochemical Pharmacology, vol. 24, pp. 1947-1952, 1975.

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