Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2007-08-28
2007-08-28
Desai, Rita (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C546S223000, C546S225000, C546S245000
Reexamination Certificate
active
10309781
ABSTRACT:
Novel compounds having activity as non-covalent inhibitors of urokinase and having activity in reducing or inhibiting blood vessel formation are provided. These compounds have at a group having a guanidino moiety or derivative thereof. These compounds are useful in vitro for monitoring plasminogen activator levels and in vivo in treatment of conditions which are ameliorated by inhibition of or decreased activity of urokinase and in treating pathologic conditions wherein blood vessel formation is related to a pathologic condition.
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Rosenberg, S., “The Urokinase-type Plasinogen Activator and its Receptor in Cancer”. In: Ann. Rep. Med. Chem. 1999, Chapter 12, vol. 34, pp. 121-128.
Alfaro-Lopez L. Josue
Levy Odile Esther
Semple Joseph Edward
Tamiz Amir P.
Dendreon Corporation
Desai Rita
Townsend and Townsend / and Crew LLP
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