Aromatic coupling process

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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C07C12175

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045213453

ABSTRACT:
4-(2-Cyano-4-nitrophenyl)phenols are prepared by reacting a 3-cyano-1-nitrobenzene having a replaceable hydrogen in the 4-position with a phenol having a replaceable hydrogen in the 4-position in an inert solvent and in the presence of a strong base. The 3-cyano-1-nitrobenzene and phenol may be substituted or unsubstituted, and preferred phenols include phenol and 2,6-dialkylphenols.

REFERENCES:
patent: 4172151 (1979-10-01), Moore
Caronna et al., Tetrahedron Letters, No. 7, pp. 657-660.

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