Aromatic compounds containing basic and acidic termini useful as

Details Aromatic compounds containing basic and acidic termini useful as Aromatic compounds containing basic and acidic termini useful as

1993-11-24

1996-06-04

Bernhardt, Emily

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514255, 514317, 514 85, 514533, 514539, 514562, 514567, 514631, 514634, 544337, 544374, 544394, 544395, 544389, 544398, 544399, 546239, 548240, 548243, 548244, 548245, 548253, 548254, 5483741, 556420, 558172, 558406, 560 29, 560 34, 560 35, 560 42, 560 47, 560 53, 562426, 562433, 562435, 562439, 562440, 562451, 564237, 564244, 564344, 568 31, 568337, A61K 31495, A61K 31225, C07D295155, C07C22938

Patent

active

055233023

ABSTRACT:
This invention relates to novel compounds containing basic and acidic termini, pharmaceutical compositions containing such compounds, processes for preparing such compounds, and to methods of using these compounds, alone or in combination with other therapeutic agents, for the inhibition of platelet aggregation, as thrombolytics, and/or for the treatment of thromboembolic disorders.

REFERENCES:
patent: 5039805 (1991-08-01), Alig et al.
patent: 5294616 (1994-03-01), Duggan et al.
Phillips et al. Cell (1991) 65, 359-362.
Hartman et al. J Med Chem (1992) 35 4640-4642.
Alig et al. J Med Chem (1992) 35 4393-4407.
Muller et al in Receptor Data for Biological Experiments (by Doods and van Meel) pp. 112-117 (1991).

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