Aromatic compounds containing basic and acidic termini useful as

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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5462714, 5462721, 548215, 548225, 548235, 548240, 548243, 548248, 514374, 514376, 514378, 514380, C07D41302, C07D26102, A61K 3144, A61K 3142

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active

055631584

ABSTRACT:
This invention relates to novel compounds containing basic and acidic termini, pharmaceutical compositions containing such compounds, processes for preparing such compounds, and to methods of using these compounds, alone or in combination with other therapeutic agents, for the inhibition of platelet aggregation, as thrombolytics, and/or for the treatment of thromboembolic disorders.

REFERENCES:
patent: 5039805 (1991-08-01), Alig et al.
patent: 5276049 (1994-01-01), Himmelsbach et al.
patent: 5281585 (1994-01-01), Himmelsbach et al.
Phillips et al., Cell (1991) 65, pp. 359-369.
Alig et al. J. Med. Chem. (1992) 35: 4393-4407.
Hartman et al. J. Med. Chem. (1992) 35: 4640-4642.

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